Programme scientifique

Toutes les sessions sont dans les salles Grand Event Rooms A et B
Les repas ont sont dans le Sunhill Dining Room
Les présentations de posters sont la salle in Grand Events Room C
Les pauses-café sont dans le Garden View Foyer

Lundi 1 juin
12:00 - 18:00	Inscription
14:00 - 17:00	CIHR Training Program in Protein Folding: Trainee Minisymposium For minisymposium schedule, click here
18:00	Souper
19:30 - 21:00	Présentations du prix Merck Frosst Mick Bhatia (McMaster) Cellular and molecular characterization of human pluripotent stem cells
21:00 pm	Mixeur d'ouverture

Mardi 2 juin
07:00	Déjeuné
	Séance 1: Protein Folding in the Cell Chair: Gergely Lukacs (McGill)
08:15	Susan Lindquist (Whitehead Institute) Happy Birthday Darwin! Protein folding propels evolution
08:50	Chris Kaiser (MIT) The Meaning and Mechanisms of Redox Homeostasis in the ER
09:25	Alan Davidson (U. of Toronto) The important role of unstructured protein regions in bacteriophage assembly
10:00	Pause-café
10:30	Jason Young (McGill) Functional diversity of Hsc70 co-chaperones
10:50	Bill Balch (Scripps) Managing folding and traffic in human misfolding disease
11:25	David Thomas (McGill) Correcting the trafficking defect of ΔF508 CFTR
12:00	Dîner
13:00 - 16:00	Temps libre
16:00	Présentation de posters I
18:00	Souper
	Séance 2: Theoretical & Computational Approaches to Protein Folding Chair: Régis Pomès (SickKids, Toronto)
19:30	Régis Pomès (SickKids, Toronto) Molecular mechanism of beta-sheet formation at water-nonpolar interfaces
20:05	Ken A. Dill (UCSF) Modeling protein stabilities and solubilities
20:40	Pause-café
21:00	Vijay S. Pande (Stanford) Simulating protein folding in vitro and in vivo on experimentally relevant timescales
21:35	Hue Sun Chan (U. of Toronto) Cooperativity in Protein Folding: Theory and Experiment
22:10 - 24:00	Pub aux posters

Mercredi 3 juin
07:00	Déjeuné
	Séance 3: Mechanisms of Protein Folding and Misfolding Chair: Charles Deber (SickKids, Toronto)
08:15	Chris Dobson (Cambridge) Protein Misfolding and Disease: From the Test Tube to the Organism
08:50	Charles Deber (SickKids, Toronto) Peptide approaches to memberane protein folding
09:25	Susan Marqusee (UC Berkeley) Manipulating the folding landscape using the optical tweezers
10:00	Pause-café
10:30	Art Horwich (Yale) Chaperone action in vitro and in an ALS model
11:05	Linda Foit (U Michigan) Optimizing protein stability in vivo offers new insights into the conflicting forces in protein evolution
11:25	Lewis Kay (U of Toronto) Seeing the invisible by solution NMR spectroscopy
12:00	Dîner
13:00 - 16:00	Temps libre
16:00	Présentation de posters II
18:00	Souper
	Séance 4: Cellular Responses to Protein Misfolding Chair: Allen Volchuk (UHN, Toronto)
19:30	Walid Houry (U of Toronto) The role of nucleotides and amino acid decarboxylases in the bacterial acid stress response
20:05	Ron Kopito (Stanford) Prion-like properties of polyglutamine amyloids
20:40	Pause-café
21:00	Randy Kaufman (U of Michigan) Interactions between protein misfolding in the ER and oxidative stress
21:35	David Ron (Skirball Inst., NYU) Prospects for tuning the Unfolded Protein Response
22:10 - 24:00	Pub aux posters

Jeudi 4 juin
07:00	Déjeuné
	Séance 5: Protein Dynamics and Disorder Chair: Scott Prosser (U Toronto)
08:15	Peter Wright (Scripps) Promiscuous proteins: folding and interactions of intrinsically disordered proteins
08:50	Julie Forman-Kay (SickKids, Toronto) Disordered Protein Interactions within Highly Dynamic Regulatory Protein Complexes
09:25	Lawrence Macintosh (UBC) Rheostatic control of gene expression: conformational flexibility and phosphorylation-dependent regulation of Ets transcription factor
10:00	Pause-café
10:30	Peter Tompa (Budapest) Unusual modes of molecular recognition by disordered proteins
11:05	George Harauz (U Guelph) Induced Secondary Structure and Polymorphism in Myelin Basic Protein, an Intrinsically Disordered Organizational Linker of the CNS
11:25	Mitsu Ikura (UHN, Toronto) STIM1-mediated store-operated calcium entry uses a protein unfolding/oligomerization-coupled mechanism?
12:00	Dîner
13:00 - 16:00	Atelier principal: Prion Protein Misfolding - *Canadian Contributions to Protein Structure and Dynamics* Organized by PrioNet Canada and the Alberta Prion Research Institute Speakers include: Avi Chakrabartty, University of Toronto; Will Guest, University of British Columbia; Michael James, University of Alberta; Nahid Jetha, University of British Columbia; Olivier Julien, University of Alberta; Nat Kav, University of Alberta; Braden Sweeting, University of Toronto; David Wishart, University of Alberta
16:00 - 17:00	Assemblée générale annuelle de la SCBBMC
18:00 - 19:00	Mixeur
19:00 - 21:30	Banquet et présentation des prix

Vendredi 5 juin
07:00	Déjeuné
	Séance 6: Protein Misfolding in Aging and Disease Chair: Neil Cashman (UBC)
08:15	Peter St. George-Hyslop (U of Toronto) Molecular insights into protein misfolding in Alzheimer’s Disease and Frontotemporal Dementia
08:50	Cynthia Lemere (Brigham and Women’s) Immunotherapy for Alzheimer's and Other Neurodegenerative Diseases
09:25	Jeff Kelly (Scripps) Restoring Proteostasis to Ameliorate Disease
10:00	Pause-café
10:30	David Westaway (U of Alberta) Attributes and Overlaps of the PrP and Shadoo proteins
11:05	Jeremy Lee (U Sask) Nanopore analysis of the interaction of metal ions and antibodies with prion proteins
11:25	David Vocadlo (SFU) Modulators of intracellular glycosylation limit microtubule-associated protein tau phosphorylation in vivo
12:00	Dîner et départ

52e Congrès annuel de la société de biochimie et de biologie moléculaire et cellulaire Le repliement des protéines : principes et maladies

Programme scientifique

52e Congrès annuel de la société de biochimie et de biologie moléculaire et cellulaire
Le repliement des protéines : principes et maladies