55th Annual Conference of the Canadian Society for Molecular Biosciences

Epigenetics and Genomic Stability

March 14 - 18, 2012
Whistler Conference Centre
Whistler, British Columbia
Canada

All sessions are held in the Sea to Sky Ballroom B
Welcome reception is in the Grand Foyer
Meals and coffee breaks are in the Grand Foyer
Poster displays are in Sea to Sky Ballroom C
Banquet and Awards Presentations are in Sea to Sky Ballroom A

 Wednesday - March 14, 2012

Registration

8:30 - 11:00 pm

Welcome Reception (Cash Bar)

 Thursday - March 15, 2012

Breakfast

Registration

Session I: Plenary and Awards Lecture
Session Chair: Jim Davie, University of Manitoba

Welcome and Keynote address
Penny Jeggo, University of Sussex
DNA Double Strand Break Repair: The Interface between Resection and Rejoining

GE Healthcare NEW Investigator Award Lecture
John Brumell, University of Toronto
Interactions of Salmonella and Listeria with the Autophagy System of Host Cells

Coffee Break

Grant and Moens Award of Excellence in Genetics
John Phillips, University of Guelph
Choosing the Right Tie: Fruit Flies, Frankenfood and Fashion

Lunch

Poster Session I or Free Time

Poster Pub and Judging (Cash Bar)

Jane E. Aubin, Chief Scientific Officer/Vice President, Research
Canadian Institutes of Health Research

Eric Marcotte, Associate Director, Regenerative Medicine and Nanomedicine
Canadian Institutes of Health Research
The Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC)

Dinner

Session II: Epigenetic Contributions to Gene Activation
Session Chair: Juan Ausio, University of Victoria

Patrick McGowan, University of Toronto
The Epigenetic Signature of Early Life

Alexander Mazo, Thomas Jefferson University
Epigenetic marks during DNA replication

Coffee Break

Toshio Tsukiyama, Fred Hutchinson Cancer Research Center
Chromatin Regulation and DNA Replication

Michael Kobor, University of British Columbia
Chromatin Regulation of Genome Function

 Friday - March 16, 2012

Breakfast

Session III: Epigenetic Mechanisms in Silencing
Session Chair: Hugh Brock, University of British Columbia

Robin Allshire, University of Edinburgh
Rebooting and Preventing the Assembly of Centromeric Chromatin

Matt Lorincz, University of British Columbia
Writers and Readers of H3K9 Methylation in Mouse ESCs: A Surprising Tail

Benjamin Martin, University of British Columbia
Histone Acetylation As a Consequence of Ongoing Transcription

Coffee Break

Barbara Panning, University of California
Polycomb Silencing in Embryonic Stem Cells

Sheila Teves, Fred Hutchinson Cancer Research Center
High-Resolution Mapping of Epigenome Dynamics

Gratien Prefontaine, Simon Fraser University, British Columbia
Smc-HD1 Mediates Transcriptional Repression of the Growth Hormone Gene in a DNA Methylated Dependent Manner

Lunch / CSMB Board Meeting

Poster Session II or Free Time

Poster Pub & Judging (Cash Bar)

Alex Robertson, Senior Scientific Project Coordinator, Next Generation Sequencing Platforms, Life Technologies
Re-revolutionizing Next Generation DNA Sequencing and the Impact to Genetics, Genomics and Translational Medicine

David Delano, Product Manager, Epigentics Illumina, Inc.
Illumina Epigenetics – Power Across the ‘Dash’ Board

CSMB Annual General Meeting

Dinner

Session IV: Chromatin Assembly, Chromosomal and Nuclear Architecture
Session Chair: LeAnn Howe, University of British Columbia

Jennifer Mitchell, University of Toronto
Nuclear Organization of RNAPII Transcription

Josée Dostie, McGill University
Hox in Motion

Coffee Break

David Bazett-Jones, Hospital for Sick Children
Global Chromatin Structure Configurations in Cellular Differentiation

Michael Hendzel, Alberta Cancer Board
Polycomb Repressor Complex 1 (PRC1) is an Upstream Component in DNA Double-Strand Break Signaling

 Saturday - March 17, 2012

Breakfast

Session V: Environment, Disease, and Genome Instability
Session Chair: Sue Varmuza, University of Toronto

Michael Skinner, Washington State
Epigenetic Transgenerational Actions of Environmental Compounds on Reproduction and Disease

Philip Hieter, University of British Columbia
Chromosome Instability (CIN) in Yeast and Cancer

Krassimir Yankulov, University of Guelph, Ontario
Telomere Position Effect and the Passing/Pausing of Replication Forks

Coffee Break

Olga Kovalchuk, University of Lethbridge
Epigenetic Changes in Radiation-Induced Genome Instability and Carcinogenesis

Igor Kovalchuk, University of Lethbridge
Transgenerational Changes in Genome Stability in Response to Stress in Plants - Epigenetic Regulation

NRC Research Press Senior Investigator Award Lecture
Michel Bouvier, Université de Montreal
Molecular Basis of G Protein-Coupled Receptor Functional Selectivity and Trafficking; New Opportunities for Drug Discovery

Lunch

Poster Session III or Free Time

Poster Pub & Judging (Cash Bar)

Session VI: Sensing and Repairing DNA Damage
Session Chair: Michael Hendzel, Alberta Cancer Board

Michael Kruhlak, National Cancer Institute
Alterations in the Chromatin Environment Following the Introduction of DNA Breaks in Living Cells

Aaron A. Goodarzi, University of Calgary
SNF2H-ACF1 Facilitates Artemis-Dependent DNA Double Strand Break Repair in Heterochromatin

Alain Verreault, Université de Montréal
Histone Acetylation and DNA Damage During Replication

Coffee Break

Susan Lees-Miller, University of Calgary
Structural Insights into the Non-Homologous End Joining (NHEJ) Pathway

Dan Gottschling, Fred Hutchinson Cancer Research Center
Age-associated Genome Instability: How Cellular Subsystems Breakdown

CSMB Banquet and Awards Presentations (Cash Bar)
2012 Arthur Wynne Gold Medal Award Lecture
Dr. Henry Friesen, Distinguished Professor Emeritus, University of Manitoba

 Sunday - March 18, 2012

Departure